Prediction: Napoli vs Lazio

Verdict: Home win

Best odds: 12/25

Bookmaker: ZetBet

Napoli’s hopes of defending their Serie A crown may have faded following last week’s stumble, but the champions remain fully focused on finishing as runners‑up when they host Lazio on Saturday evening.

With six rounds remaining, the Partenopei sit well adrift of leaders Inter Milan, while their visitors arrive in Naples mired in mid‑table and fresh from another domestic setback.

Napoli

After stringing together five consecutive league victories, Napoli’s slim title ambitions were effectively extinguished last weekend. Antonio Conte’s side could manage only a 1–1 draw away to Parma, allowing Inter to restore a nine‑point cushion at the summit after a dramatic comeback win of their own in Como.

Napoli were architects of their own misfortune at the Tardini, conceding early through a defensive lapse before Scott McTominay once again stepped up to rescue his side with an equaliser. Despite dominating the closing stages and carving out opportunities, the champions were unable to find the decisive goal their territorial control merited.

Even so, Napoli remain favourites to finish second, having charged past AC Milan with a formidable spell of form. Conte’s men have collected 16 points from the last six Serie A matchdays—more than any other team—and have been imperious at Stadio Maradona. They are unbeaten at home in the league since December 2024, when Lazio claimed a narrow 1–0 win, and have since recorded 19 victories alongside seven draws on their own turf.

That home defeat to Lazio stands in contrast to more recent success against the Biancocelesti. Napoli emerged victorious in the reverse fixture in Rome, with first‑half strikes from Leonardo Spinazzola and Amir Rrahmani proving decisive at the Olimpico.

Team News

Rrahmani could return to the matchday squad after seven games out with a hamstring injury, but captain Giovanni Di Lorenzo remains sidelined until next week’s fixture against Cremonese. Romelu Lukaku, David Neres and Antonio Vergara are also unavailable, leaving Napoli’s attacking responsibility firmly in the hands of Rasmus Højlund and his supporting cast.

McTominay is set to continue alongside Kevin De Bruyne in midfield support, having found the net three times in his last five league appearances. His late runs from deep have increasingly become a defining feature of Conte’s attack.

Lazio

Despite losing January’s reverse fixture, Lazio can draw confidence from their recent travels to Naples, having won each of their last three league matches there—matching the total they had managed across the previous 20 visits combined.

Recent form, however, suggests maintaining that run will be difficult. Lazio’s 1–0 defeat away to Fiorentina on Monday night left the capital club rooted in ninth place, a full 13 points behind city rivals Roma in the race for European qualification. That lacklustre performance at Stadio Franchi epitomised a difficult domestic campaign.

With league ambitions largely extinguished, Lazio’s focus has shifted to the Coppa Italia, where they remain alive ahead of the second leg of their semi‑final against Atalanta next Wednesday after a 2–2 draw in the first meeting. Securing a trophy may be Maurizio Sarri’s primary objective before a likely summer departure, particularly with patience continuing to wear thin over their Serie A displays.

Away from home, Lazio’s problems have been stark. They have failed to score in 10 of their 16 league road trips this season, and even Sarri has acknowledged his frustration with the side’s blunt attacking output. While Napoli’s captain is still sidelined, Lazio received a boost on Monday as their own skipper returned slightly ahead of schedule, with Mattia Zaccagni expected to feature at the Maradona.

Team News

There are still significant absences. Adam Marušić and Nicolò Rovella remain unavailable, while first‑choice goalkeeper Ivan Provedel has been joined on the sidelines by third‑choice Alessio Furlanetto.

Centre‑backs Mario Gila and Samuel Gigot have returned to training, but Daniel Maldini remains a major doubt. Should he miss out, Boulaye Dia is likely to edge ahead of Tijjani Noslin and Petar Ratkov in the forward line.

Conclusion

After a brief stumble, Napoli are well placed to return to winning ways against a Lazio side drifting toward the end of a turbulent campaign. While the visitors’ attention may already be drifting toward their cup ambitions, Conte’s men are closing the season at full speed in Serie A.

With home form once again formidable, Napoli should have enough to secure victory and tighten their grip on second place.

Verdict: Home win

Best odds: 12/25

Bookmaker: ZetBet