Thomas Tuchel will expect Chelsea to mark his 50th Champions League game as a boss with a win at Lille and Juve will be favourites to knock Villarreal out on Wednesday.
There is huge uncertainty at Stamford Bridge after Roman Abramovich put the club up for sale before having his assets frozen by the United Kingdom government, but the London club have won four consecutive games.
The holders travel to Lille for the second leg of the round-of-16 tie with a 2-0 lead courtesy of goals from the in-form Kai Havertz and Christian Pulisic.
Juve and Villarreal will start their showdown at the Allianz Stadium locked at 1-1 after Dani Parejo equalised following Dusan Vlahovic’s early strike.
Stats Perform picks out the standout Opta data ahead of the two games.
Lille v Chelsea
Havertz has become the Blues’ main man, scoring four goals in his past three matches and six in seven.
Chelsea head coach Tuchel has won 31 of his 49 matches and can set a record for the most victories in his first 50 games as a boss in the competition with another success in Lille, as he is currently level with Zinedine Zidane’s tally.
Lille’s chances of forcing their way back into the tie appear to be slim, as not only do they trail by two goals, they have lost their past three Champions League games against the Premier League club.
They have also been eliminated from each of their three previous European knockout ties after losing the first leg.
The last side to progress against Champions League holders after failing to score in the opening leg was Arsenal versus Milan in 2007-08, with the first leg a goalless draw.
Each of Chelsea’s past 11 wins in the Champions League have come with a clean sheet, 10 of which have come under Tuchel in just 14 matches.
Juventus v Villarreal
January signing Vlahovic set a record for the quickest goal by a Champions League debutant when he was on target after only 32 seconds of the first leg.
Juve are without a win in each of their past seven first-leg games in the Champions League (D3 L4), going on to be eliminated from four of their previous five knockout ties in the competition.
Villarreal have won their past two away games in the Champions League, the same number of victories as they managed across the 15 such matches beforehand.
Juve have only lost three of their previous 23 Champions League matches at home to Spanish sides in this competition, winning 12 and drawing eight.
This will be Villarreal’s first visit to Juventus in any competition as they scent a place in the quarter-finals.
Juan Cuadrado is in line to make his 50th appearance for Bianconeri in the Champions League. He has provided 11 assists for the Serie A giants in the competition, which is the most by any player in the period since he first joined the club in 2015.
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